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'Inside the O'Briens' by Lisa Genova is a heart-wrenching story that delves into the lives of the O'Brien family as they navigate the challenges of Huntington's Disease. Joe O'Brien, a Boston cop and father of four, is diagnosed with Huntington's Disease, a hereditary condition that will impact not only his life but also the future of his children. The book follows the family's journey as they come to terms with the diagnosis, make difficult decisions, and support each other through the struggles that come with the disease. Genova's writing style beautifully captures the emotional turmoil and complexities of living with a genetic neurodegenerative disease.

If you liked Inside the O'Briens, here are the top 4 books to read next:

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  1. #1

    Every Note Played by Lisa Genova
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    Lisa Genova, a neuroscientist and great author, has written another book about a neurological illness, this time tackling ALS as seen through the eyes of a divorced couple. The ex-husband, a brilliant pianist with a successful career, is robbed of everything important to him in life including body functioning by ALS. His ex-wife, also an exceptionally talented pianist, reluctantly becomes his caregiver when she learns of his disease and prognosis. The book impressively delves into emotional growth, forgiveness, and the challenges of a troubled relationship plagued by past grievances and lack of communication.

    Another solid book by Genova, "Every Note Played" focuses on ALS and the strained relationship between Richard and Karina, his ex-wife. The story beautifully portrays the tragedy of ALS and the importance of communication, showcasing the growth and complexities of both characters as they navigate their past and present struggles while dealing with the devastating effects of the disease.

    If Karina had grown up fifteen kilometers down the road in either direction north or south, in Gliwice or Bytom instead of Zabrze, her whole life would be different. Even as a child, she never doubted...

  2. #2

    Left Neglected by Lisa Genova
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    'Left Neglected' by Lisa Genova follows the story of Sarah Nickerson, a high-powered executive and mother of three, who suffers a traumatic brain injury in a car accident, leading to a condition called Left Neglect. The book explores Sarah's journey of recovery, adaptation to her new reality, and reevaluation of her priorities in life. Through the eyes of Sarah, readers get a glimpse into the challenges of living with a neurological condition and the impact it has on her relationships and sense of self. Genova's writing style captures the emotional struggles and growth of the protagonist, offering a poignant and insightful narrative that delves into themes of family, identity, and resilience.

    The actual alarm clock reads 5:06, about an hour before the time I set it for. Resigned to getting up now, I click the alarm mode to Off. I honestly can’t remember the last time I woke to the sound of...

  3. #3

    Still Alice by Lisa Genova
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    'Still Alice' by Lisa Genova is a heart-wrenching story that follows the life of Alice Howland, a talented Harvard professor diagnosed with early-onset Alzheimer's disease. The novel chronicles Alice's journey as she rapidly loses her memory and sense of self, all written from her own point of view. The reactions of Alice's husband, children, colleagues, and friends are portrayed in a human and illuminating manner, showcasing the impact of the disease on their lives. provides a compassionate and insightful look into the struggles of living with Alzheimer's, offering a unique perspective on the disease.

    Alice sat at her desk in their bedroom distracted by the sounds of John racing through each of the rooms on the first floor. She needed to finish her peer review of a paper submitted to the Journal of...

  4. #4

    Cutting for Stone by Abraham Verghese
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    Cutting for Stone by Abraham Verghese is an enthralling and epic story that follows the lives of Marion and Shiva Stone, conjoined twins born in Ethiopia. The narrative explores their tumultuous journey from birth, their upbringing in a mission hospital, their separation, and their individual paths towards becoming accomplished doctors. The book delves into themes of family, betrayal, forgiveness, and the complexities of human relationships, set against the backdrop of Ethiopia, New York, and the world of medicine. Verghese's writing style is described as beautifully crafted, meticulously detailed, and enriched by his medical knowledge, which enhances the authenticity of the hospital scenes portrayed in the novel.

    THOMAS STONE HAD a reputation at Missing for being outwardly quiet but intense and even mysterious, though Dr. Ghosh, the hospital's internal medicine specialist and jack-of-all-trades, disputed that ...

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